Company Information

Presentation

Sociedad Europea de Análisis Diferencial de Movilidad SL (SEADM) is a Spanish SME founded in February 2005 with the aim of developing a new generation of analytical instruments able to detect trace elements at the subfemtogram level, both in the atmosphere or within the body fluids, based on the know-how of its technical consultant and co-founder Juan Fernandez de la Mora, Yale University professor.

Areas of know-how

SEADM technology is based on the integration of commercial mass spectroscopy and two areas of proprietary know-how:

Differential Mobility Analysis (DMA). Seadm develops Differential Mobility Analyzer (DMA) tailored to replacement of LC equipments, showing excellent characteristics of MS integration, speed, sensitivity and resolution.
An ion source for ionisation of vapors, based on the Electrospray ionization (ESI). The ion source, or electrospray ionizer, readily interfaces with the Differential Mobility Analyzer (DMA), and allows on-line analysis of vapours, for DMA-MS applications.

The company holds 11 patents in the area, and has the exclusive world-wide licence for 2 patents on mobility analysis property of Yale University (USA), and sublicensed by the US company NanoEngineering.

Activities

Since 2005, SEADM has completed or is currently developing the following projects:

EXPLOSIVE TRACE DETECTION
- Industrial research activities in the field of explosive detection from 2005, all of them developed in partnership with Fundación CARTIF:
  - AROMA project, jointly funded by the Spanish Ministry of Industry (Profit program) and Ministry of Defence (Coincidente program).
  - OLFATO project, funded by the Castilla y Leon Regional Government (ADE line 4), in 2006-2007.
  - DETEV project, funded by the Spanish Ministry of Industry in 2007-2009.
  - SIMDE project, funded by the Castilla y León Regional Government (ADE line 4) in 2007-2009.
  - CARGO project, under subcontract from the related company SEDET, which started in 2008 and is currently under development.
  - EFFISEC program, an FP7 integration program from the First Security Call (2009-2013), led by Morpho, where Seadm develops a trace detector based on mass spectrometry.
- The company has developed a Demonstrator showing detection capability for vapour traces of explosive in the atmosphere at concentrations of 1 ppq (parts per quatrillion) .
DIFFERENTIAL MOBILITY ANALYSIS (DMA) DEVELOPMENTS
- MAIMS Program (Mobility Analysis Integrated with Mass Spectrometry), an eighteen months program which began in September 2006, is an initiative to couple a Differential Mobility Analyzer (DMA) to an API Mass Spectrometer, in order to increase its resolution capability for biological analysis. MAIMS is an international Canadeka program and is partially funded by the Spanish Ministry of Industry within the 2004-2007 National R&D Plan.
- VEAME Program, which began in June 2009 and ended in December 2010. Its aim has been to develop an electronic Differential Mobility Analyzer (DMA). VEAME was supported by the Spanish Ministry of Industry. Project number TSI-020100-2009-53.
- EVA Program, which began in February 2010 and extended for 18 months. Its aim has been to couple Differential Mobility Analyzers (DMAs) in serie, in order to obtain a mobility filtering device with a resolution in the order of 1,000.
- VEAME DOBLE Program, which began in May 2011 and will be developed in 36 months. Its aim has been to develop a double electronic Differential Mobility Analyzer (DMA). VEAME DOBLE is supported by the Spanish Ministry of Industry, Energy and Tourism, within the National Plan for Scientific Research, Development and Technological Innovation 2008-2011 (Subprogram Avanza Competitividad I+D+I). Project number TSI-020100-2011-34.

VAPOR IONIZER BY MEANS OF AN ELECTROSPRAY CLOUD (SESI) DEVELOPMENT
- Development of an ion source for ionization of vapors based on an electrospray cloud (SESI) directly integrated to the Differential Mobility Analyzer (DMA). An internally funded program, its aim is to increased ten fold the ionization efficiency of an Electrospray source closely integrated with a Differential Mobility Analyzer (DMA).

IDOC Program (Odour Diagnosis of Cancer)
- IDOC Program (Odour Diagnosis of Cancer), under subcontract from the company Ilía Systems S.L., started in June 2010 and will be developed for 18 months. The aim of Seadm participation is to produce a Differential Mobility Analyzer (DMA) and its interface with a TOF mass spectrometer, and to investigate techniques for determination of the cancer olfactory bouquet. IDOC is currently supported by the Spanish Ministry of Industry, inside of the National Plan for Scientific Research, Development and Technological Innovation 2008-2011. Project number TSI-020100-2010 -12.

Resources

SEADM has the following resources:

Personnel: 15 engineers.
Laboratory: Installed in Fundación CARTIF facilities, Seadm laboratory covers a 250 m2 area, and includes a Sciex Q-Star XL TOF mass spectrometer, a Sciex API 5000 triple quadrupole, as well as a single quadrupole Shimadzu LCMS 2010.